In vitro research, 25C-NBOMe has become revealed to exhibit cytotoxicity on neuronal cell strains SH-SY5Y, PC12, and SN471, as well as the compound was much more potent than methamphetamine at lowering the visibility in the respective cells; the neurotoxicity of your compound entails activation of MAPK/ERK cascade and inhibition of Akt/PKB signalin